Synthesis of Fluorogenic Substrates for Detection of a-L-Iduronidase Deficiency in Mucopolysaccharidosis

碩士 === 國立清華大學 === 化學系 === 88 === A novel and efficient route toward the formal synthesis of 4-methylcoumarin-7-yl α-L-idopyranosiduronic acid 1, a fluorogenic substrate for assay of α-L-iduronidase activity in Mucopolysaccharidosis, began with the b-L-idofuranoses 21 or 22, available from diacetone...

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Bibliographic Details
Main Authors: Chien-Sheng Chen, 陳建盛
Other Authors: Chun-Chen Liao
Format: Others
Language:zh-TW
Published: 2000
Online Access:http://ndltd.ncl.edu.tw/handle/89807915819551463990