Germline and somatic mutation of hMSH2 gene conferring the replication error phenotype of two hereditary nonpolyposis colorectal cancer families

碩士 === 國防醫學院 === 生物及解剖學研究所 === 88 === Hereditary nonpolyposis colon cancer (HNPCC) is an autosomal inherited cancer syndrome characterized by germline and somatic mutations of DNA mismatch repair genes and subsequent accumulation of replication errors (RER, as indicated by microsatellite instability...

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Bibliographic Details
Main Authors: Rui-Len Huang, 黃瑞蘭
Other Authors: Tang-Yuan Chu
Format: Others
Language:zh-TW
Published: 2000
Online Access:http://ndltd.ncl.edu.tw/handle/14414760039200158164