NMR Studies of the Conformation of E. coli Dihydrofolate Reductase Complexes and the Kinetics of Isotope Exchange Reactions of Malonic Acids
博士 === 國立成功大學 === 化學系 === 87 === Abstract Multiple 13C-labelled methotrexate (MTX), [2,N10-CH3-13C2] metho-trexate and 15N-labelled [1,3,2-NH2-15N3]folate and [1,3,2-NH2-15N3] methotrexate have been synthesized. The two 15N-labelled compounds have been used to directly measure the pKa...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
1999
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| Online Access: | http://ndltd.ncl.edu.tw/handle/80257507551268279534 |