Asymmetric Conjigate Addition of Thiols to α, β-Unsaturated N-Acyloxazolidnones
博士 === 高雄醫學大學 === 藥學研究所 === 84 === The conjugate addition of(5S)-5-phenyl-N-methacryloyl oxazolidin-2-one(E2-4) with thioacetic acid in the presence of TiCl4 gave the addition adducts in 87% yield and 14% de. When this reaction was carried out in the absence of TiCl4, good diastereoselectivity(94% d...
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Format: | Others |
Language: | zh-TW |
Published: |
1996
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Online Access: | http://ndltd.ncl.edu.tw/handle/95612433237669568535 |