Mechanism of the potentiation effect of acetylcholine (ACh) on the thyrotropin releasing hormone (TRH)-induced c-fos mRNA expression
碩士 === 國立陽明大學 === 生物化學研究所 === 83 === GH3腦下腺垂體癌細胞株,經acetylcholine (ACh)24小時前處理後,會增強thyrotropin-releasinghormone(TRH)引發prolactin及C-fos基因表現。本篇進一步探討ACh對TRH刺激C-fos基因表現促進作用機轉。 我們發現以TMB-8(細胞內鈣離子流動抑制劑),thapsigargin(calcium/ATPase抑制劑,可以枯竭細胞內貯藏的鈣離子),verapamil或nifedipine(s...
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Format: | Others |
Language: | zh-TW |
Published: |
1995
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Online Access: | http://ndltd.ncl.edu.tw/handle/03276673446680222249 |