Modulation of N-Methyl-D-Asparate Receptor by Transient Receptor Potential Melastatin Type-2 Regulates Neuronal Vulnerability to Ischemic Cell Death

Neuronal vulnerability to ischemia is dependent on the balance between pro-survival and pro-death cellular signaling. In the latter, it is increasingly appreciated that toxic Ca2+ influx can occur not only via postsynaptic glutamate receptors, but also through other cation conductances. One such con...

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Bibliographic Details
Main Author: Alim, Ishraq
Other Authors: Tymianski, Michael
Language:en_ca
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1807/65630