In Vitro Modeling of Pancreatic Duct Cell Carcinogenesis

Pancreatic adenocarcinoma (PDAC) putatively arises from the pancreatic duct, thus usage of the normal human pancreatic duct epithelial (HPDE) cell line is an ideal model to examine the successive accumulation of genetic alterations involved in carcinogenesis. KRAS mutations have been reported in 90...

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Bibliographic Details
Main Author: Leung, Lisa
Other Authors: Tsao, Ming-Sound
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/65513