The Requirement for Oxygen in the Maturation and Secretion of Soluble urokinase Plasminogen Activator Receptor (uPAR)

The Requirement for Oxygen in the Maturation and Secretion of Soluble urokinase Plasminogen Activator Receptor (uPAR)

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TTumor hypoxia (poor oxygenation) adversely affects patient prognosis by promoting therapeutic resistance and an aggressive tumor phenotype. We aimed to understand how urokinase plasminogen activator receptor (uPAR), a cysteine-rich protein implicated in the malignant phenotype and poor patient prog...

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Bibliographic Details
Main Author: Rumantir, Ryan Allister
Other Authors: Koritzinsky, Marianne
Language:en_ca
Published: 2013
Subjects:
Biochemistry
Oncology
0487
0307
Online Access:http://hdl.handle.net/1807/43321

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