The Requirement for Oxygen in the Maturation and Secretion of Soluble urokinase Plasminogen Activator Receptor (uPAR)
TTumor hypoxia (poor oxygenation) adversely affects patient prognosis by promoting therapeutic resistance and an aggressive tumor phenotype. We aimed to understand how urokinase plasminogen activator receptor (uPAR), a cysteine-rich protein implicated in the malignant phenotype and poor patient prog...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/43321 |