Mechanisms of Right-ventricular Dysfunction in a Rat Model of Chronic Neonatal Pulmonary Hypertension
Chronic neonatal pulmonary hypertension (PHT) frequently presents with rightventricular (RV) dysfunction. In neonatal rats exposed to chronic hypoxia, RV dysfunction is reversed by sustained rescue treatment with a Rho-kinase (ROCK) inhibitor – the caveat being systemic hypotension. We therefore exa...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/42849 |