Mechanisms of Glucagon-like Peptide-2-mediated Effects on Intestinal Barrier Function in Health and Irinotecan-induced Enteritis

Glucagon-like peptide-2 (GLP-2) is an intestinal hormone that promotes gut growth through an insulin-like growth factor (IGF)-1 and intestinal epithelial (IE)-IGF-1 receptor (R)-dependent pathway. GLP-2 also promotes epithelial barrier function by as yet unknown mechanisms. I hypothesized that GLP-2...

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Bibliographic Details
Main Author: Dong, Charlotte
Other Authors: Brubaker, Patricia
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/42819