TRADD Mediates Inflammatory Responses in the Cytoplasm and Tumor Suppression in the Nucleus

TNF is a proinflammatory cytokine whose pleiotropic biological properties are signaled through the receptor TNFR1. Activation of this signaling pathway has been implicated in a broad range of biological functions, including host defense, inflammation, apoptosis, autoimmunity, and cancer. TRADD is an...

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Bibliographic Details
Main Author: Chio, Iok In Christine
Other Authors: Mak, Tak Wah
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/36276