DNA Damage-dependent Regulation and Function of akt-1 in Caenorhabditis elegans

The roundworm Caenorhabditis elegans possesses a single, conserved phosphatidylinositol 3-kinase (PI3K) signaling pathway that regulates somatic developmental decisions and lifespan through the Insulin-like receptor tyrosine kinase (RTK) DAF-2, the class I PI3K AGE-1 and the 3-phosphoinositide-depen...

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Bibliographic Details
Main Author: Perrin, Andrew
Other Authors: Derry, William Brent
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/35752