DNA Damage-dependent Regulation and Function of akt-1 in Caenorhabditis elegans
The roundworm Caenorhabditis elegans possesses a single, conserved phosphatidylinositol 3-kinase (PI3K) signaling pathway that regulates somatic developmental decisions and lifespan through the Insulin-like receptor tyrosine kinase (RTK) DAF-2, the class I PI3K AGE-1 and the 3-phosphoinositide-depen...
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Language: | en_ca |
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2012
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Online Access: | http://hdl.handle.net/1807/35752 |