Characterization of N-terminal Myc Ubiquitylation and the Novel Oncogene CUL7
Myc is an oncogene that is commonly deregulated in human cancers. Mechanistic studies reveal that Myc is a transcription factor that interacts with a protein partner called Max. Heterodimerization and the formation of the Myc:Max complex enables Myc:Max to bind to the E-box and subsequently regulate...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/35715 |