Evaluating the Interaction of HIV and the Immune System in Mucosal Tissues
90% of Human Immunodeficiency Virus (HIV) infections are acquired across the genital or gastrointestinal mucosa, and infection leads to profound depletion of CD4+ lymphocytes. Antiretroviral therapy can restore blood CD4+ T cells. However, immune dysfunction and defects in mucosal antimicrobial defe...
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Language: | en_ca |
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2013
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Online Access: | http://hdl.handle.net/1807/35172 |