The Mechanism of Discoidin Domain Receptor 1 Mediated Vascular Calcification
Introduction: Activation of Runt Related Transcription Factor 2 (RUNX2) is required for transdifferentiation of Vascular Smooth Muscle Cells (VSMCs) into a calcifying osteoblast-like phenotype. Our lab showed that deletion of Discoidin Domain Receptor 1 (Ddr1), decreased atherosclerotic vascular cal...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/35146 |