Harnessing Mitochondria-penetrating Peptides for the Organellar Delivery of Small Molecule Drugs

Mitochondria play essential roles in numerous cellular processes, including oxidative phosphorylation and apoptotic initiation. As a result, organellar dysfunction has been implicated in several pathologies such as cancer, diabetes and neurodegenerative diseases. The opportunity to deliver compounds...

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Bibliographic Details
Main Author: Fonseca, Sonali
Other Authors: Kelley, Shana O.
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/34000