Molecular Mechanisms Involved in Insulin- and Leptin-mediated Regulation of Hypothalamic Proglucagon Gene Expression and Action of Glucagon-like Peptides on Hypothalamic Neuropeptides

The hypothalamus is a central regulator of energy homeostasis. Recently, proglucagon-derived peptides have emerged as potential appetite regulators. The proglucagon gene is expressed in the periphery and also in selective hypothalamic neurons. The regulation of hypothalamic proglucagon by two key re...

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Bibliographic Details
Main Author: Dalvi, Prasad S.
Other Authors: Belsham, Denise
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33973