Reactivity of Aziridine Aldehyde Dimers and their Utility in the Synthesis of Peptidomimetics

Amino aldehydes are important building blocks in organic synthesis. However, due to the innate propensity for condensation to occur upon combination of aldehydes and amines, uprotected amino aldehydes are unstable. One exception to this is the existence of dimeric aziridine aldehydes. We have shown...

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Bibliographic Details
Main Author: Assem, Naila Magdy
Other Authors: Yudin, Andrei
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33912