PAKs 1 & 3 Control Postnatal Brain Development and Cognitive Behaviour through Regulation of Axonal and Dendritic Arborizations

The molecular mechanisms that coordinate postnatal brain enlargement, synaptic properties and cognition remain an enigma. This study demonstrates that neuronal complexity controlled by p21-activated kinases (PAKs) is a key determinant for postnatal brain enlargement and synaptic properties. Double k...

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Bibliographic Details
Main Author: Huang, Wayne
Other Authors: Jia, Zhengping
Language:en_ca
Published: 2012
Subjects:
PAK
Online Access:http://hdl.handle.net/1807/33708