Characterizing Changes in the Transcriptional Networks underlying Pluripotency in Mouse Embryonic Stem Cells upon the Induction of Differentiation
Mouse embryonic stem cells (mESCs) are pluripotent cells capable of differentiating into all three germ layers present in the adult mouse. In this thesis, I have investigated the transcriptional changes that mESCs undergo as they are induced to differentiate towards the mesoderm lineage by 2i/LIF wi...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33522 |