ED-A Fibronectin: A Storage Site for Latent TGFB-1 in the Myofibroblast Matrix?
Fibrosis, a major cause of organ failure, has no effective therapy available. Responsible for fibrosis are myofibroblasts. Mechanical stress, TGF myofibroblast differentiation, however the exact link remains elusive. I hypothesize that ED-A FN stores the latent TGF -1 in the ECM by interacting with...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32532 |