Brain CYP2D6 and its role in Neuroprotection against Parkinson's Disease
The enzyme CYP2D6 can metabolize many centrally acting drugs and endogenous neural compounds (e.g. catecholamines); it can also inactivate neurotoxins such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 1,2,3,4-tetrahydroisoquinoline (TIQ) and β-carbolines that have been associated with Par...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/31853 |