Vector Specific Tolerance Induction for Airwary Gene Therapy
The success of adenoviral mediated airway gene therapy is hindered by host immune responses against adenoviral vectors. Helper-dependent adenoviral vectors (HD-Ad) are devoid of viral coding sequences and have an improved safety profile compared to earlier generation adenoviral vectors. However, int...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/31809 |