Assessing the Combined Effect of Targeting ILK Signaling and Chemotherapy in Rhabdomyosarcoma

The pediatric sarcoma alveolar rhabdomyosarcoma (ARMS) is highly aggressive with a poor prognosis for diagnosed patients. Here, we demonstrate that targeting the unique oncogene integrin-linked kinase (ILK) in ARMS cells in conjunction with the common chemotherapy agent vincristine, a synergistic ef...

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Bibliographic Details
Main Author: Wong, Dennis Kachun
Other Authors: Malkin, David
Language:en_ca
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1807/31640