Assessing the Combined Effect of Targeting ILK Signaling and Chemotherapy in Rhabdomyosarcoma
The pediatric sarcoma alveolar rhabdomyosarcoma (ARMS) is highly aggressive with a poor prognosis for diagnosed patients. Here, we demonstrate that targeting the unique oncogene integrin-linked kinase (ILK) in ARMS cells in conjunction with the common chemotherapy agent vincristine, a synergistic ef...
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Language: | en_ca |
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2011
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Online Access: | http://hdl.handle.net/1807/31640 |