Interferon Regulatory Factor-9 (Irf-9) Mediates Short Term Host Protection, But Promotes Long Term Immune Injury in Evolution of Myocarditis Leading to Dilated Cardiomyopathy
Evolution of viral myocarditis to dilated cardiomyopathy (DCM)represents a delicate balance between host innate immunity and T-cell acquired immunity. IRF-9 is a key member of a transcription factor family that regulates type I interferon (IFN) production, critical for innate antiviral protection. R...
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| Language: | en_ca |
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2007
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| Online Access: | http://hdl.handle.net/1807/30051 |