Characterization of the Physiological Role of PDZ-RhoGEF in Drosophila and Mice
Biological outputs of insulin/IGF signaling are regulated through essential mediators, such as IRSs, PI3-kinase, and PKB/Akt. These mediators serve critical roles in signal propagation, feedback, and as junctions for crosstalk with other pathways. Abnormal insulin/IGF signaling results in disease, s...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/29969 |