The Role of the Retinoblastoma Protein Family in Skeletal Myogenesis
The retinoblastoma tumor suppressor (pRb) is thought to orchestrate terminal differentiation by inhibiting cell proliferation and apoptosis and stimulating lineage-specific transcription factors. In this thesis I have shown that in the absence of pRb, differentiating primary myoblasts fused to form...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29688 |