Role of Vascular Endothelial Growth Factor-A in Diabetic Kidney Disease

Vascular endothelial growth factor-A (VEGF) is required for endothelial cell differentiation and survival. To investigate the renoprotective properties of VEGF in diabetes an inducible Cre-loxP gene targeting system was used to excise VEGF from podocytes of adult mice (VEGFKO). Diabetes was induced...

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Bibliographic Details
Main Author: Sivaskandarajah, Gavasker
Other Authors: Quaggin, Susan E.
Language:en_ca
Published: 2011
Subjects:
Cre
Online Access:http://hdl.handle.net/1807/29625