Role of TAp73 in the Transformation of Mouse Ovarian Surface Epithelium
Tumour suppressor 73 (Trp73) gene shares structural and functional homology with p53. Trp73 encodes multiple isoforms with opposing effects. The TAp73 isoform is a transcription factor and is classified as a tumour suppressor where as the DNp73 isoform is a putative oncogene. Imbalance of the two op...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29575 |