Molecular Characterization of the von Hippel-Lindau Ubiquitin Ligase

Marking proteins for degradation by the proteasome is a classical function of ubiquitination. This process of covalent attachment of a chain of ubiquitin molecules to target proteins is governed by the ubiquitin-activating enzyme (E1), the ubiquitin-conjugating enzyme (E2) and the ubiquitin ligase (...

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Bibliographic Details
Main Author: Sufan, Roxana Ioana
Other Authors: Ohh, Michael
Language:en_ca
Published: 2009
Subjects:
VHL
HIF
Online Access:http://hdl.handle.net/1807/26478