Regulation of MDM2 and the p53 Family by the NEDD8 Pathway
NEDD8 is an ubiquitin-like protein sharing approximately 60% amino acid identity with ubiquitin and has biological roles in cell cycle progression, viability and development. Recently, a number of oncoproteins and tumor suppressors have been identified as NEDD8 substrates, including MDM2 and p53....
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/26258 |