Age Related Tissue Fibrosis During Fracture Repair Is Mediated by Wnt/β-catenin Signaling

The regenerative potential of tissue injury declines with age. Recently, a significant role for Wnt/β-catenin signaling has been shown in tissue specific stem cell aging, leading to increased tissue fibrosis. Wnt/β-catenin signaling regulates the differentiation of multipotent mesenchymal stem cel...

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Bibliographic Details
Main Author: Silkstone, David
Other Authors: Benjamin, Alman
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25802