Strain and Sex Differences in the Hepatotoxicity of 4-Aminobiphenyl in the Mouse

Strain and Sex Differences in the Hepatotoxicity of 4-Aminobiphenyl in the Mouse

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Recent studies from our laboratory on the aromatic amine carcinogen, 4-aminobiphenyl (ABP) have shown a significantly lower prevalence of ABP-induced liver tumors in male mice lacking the N-acetyltransferases, and a dramatically lower prevalence in females than in males, but no association of tumor...

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Bibliographic Details
Main Author: Emami, Arian
Other Authors: Grant, Denis M.
Language:en_ca
Published: 2010
Subjects:
Aromatic amine
Cytotoxicity
4-Aminobiphenyl
Tumorigenesis
4-ABP
Mouse strain
Hepatotoxicity
Gender disparity
Strain disparity
Chemical carcinogenesis
Hepatocellular carcinoma
HCC
Carcinogenesis
ABP
Online Access:http://hdl.handle.net/1807/25567

Internet

http://hdl.handle.net/1807/25567

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