Neuropathology of Post-stroke Depression: Possible Role of Inflammatory Molecules and Indoleamine 2,3-dioxygenase

The study evaluated whether the activity of the indoleamine 2,3 dioxygenase (IDO) enzyme is increased post-stroke and contributes to the development of post-stroke depression (PSD) via tryptophan (TRP) depletion and neurotoxic kynurenine (KYN) metabolite production. The activity of IDO was measured...

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Bibliographic Details
Main Author: Wong, Amy
Other Authors: Lanctôt, Krista
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25520