The Role of Discoidin Domain Receptor 1 (Ddr1) on Macrophages in Adhesion and Cytokine Production

Atherosclerosis is an inflammatory disease of the cardiovascular system. Discoidin domain receptor 1 is a receptor tyrosine kinase that binds collagens. Previous work in our lab has shown that deleting DDR1 in a mouse model results in attenuation of atherosclerosis, with fewer macrophages in the p...

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Bibliographic Details
Main Author: Britto, Karen Elma
Other Authors: Bendeck, Michelle
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25438