The Role of Von-Hippel Lindau (VHL) protein in Regulating Cell Cycle Progression and the Expression of Fibronectin in the Human Placenta

Von Hippel Lindau (VHL) is a tumour suppressor protein classically known to target the α subunit of hypoxia inducible factor (HIF) for proteasomal degradation. Emerging evidence has underscored a novel role for VHL in both cell cycle regulation and extracellular matrix assembly. Herein, we provide e...

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Bibliographic Details
Main Author: Deda, Livia
Other Authors: Caniggia, Isabella
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/24558