Role of FANCM in Alternative Lengthening of Telomeres (ALT) Human Cells

Most immortal human cells maintain their telomeres by up-regulating the enzyme telomerase. Approximately 10-15% of immortal cells maintain their telomere lengths by a recombination-based mechanism termed alternative lengthening of telomeres (ALT). Human ALT cells are characterized by ALT associated...

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Bibliographic Details
Main Author: Al Murshedi, Fathiya
Other Authors: Meyn, M. Stephen
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/24237