Disruption of Epigenetic Regulatory Elements and Chromosomal Alterations in Patients with Beckwith-Wiedemann Syndrome
Genomic imprinting refers to the parent-of-origin specific monoallelic expression of a gene. Imprinted genes are often clustered in the genome and their expression is regulated by an imprinting centre (IC). ICs are regions of DNA that propagate the parental specific regulation of gene expression, w...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/19296 |