Solid Molecular Dispersions of Itraconazole for Enhanced Dissolution and Controlled Drug Delivery
The purpose of this study was to investigate the formation of solid molecular dispersions of Itraconazole (ITZ) in a number of glassy polymers including PVP, crospovidone, PVP-EC, HPMCAS and HPMCAS-PEO to enhance its dissolution and achieve release control. Polarizing light microscopy was found to b...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/18761 |