The Tumour Suppressor p27kip1 Interacts with NF-kB Activator IKK and Plays a Role in Inflammation
The tumour suppressor p27kip1 (p27) is a potent inhibitor of cell growth and proliferation. We identified NF-κB activator, IKKα, as a novel interacting partner of p27 in a protein microarray screen. Both the IKKα and IKKβ components of the IKK complex were mapped to the C-terminal domain of p27. To...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/18146 |