Application of Quantitative Structure-activity Relationships to Investigate Xenobiotic Cytotoxicity Mechanisms in Hepatocyte Systems

Hepatotoxicity is a serious adverse health effect caused by drugs and other chemical toxins generally detected in the later stages of drug development or in whole animal studies. Thus, development of screening approaches available for earlier identification of hepatotoxic molecules is necessary. A...

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Bibliographic Details
Main Author: Chan, Katherine
Other Authors: O'Brien, Peter J.
Format: Others
Language:en_ca
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1807/17290