Endothelial Injury In Cardiac Transplantation: The Role Of Endothelin Antagonism And Protein Kinases

BACKGROUND: Endothelial dysfunction is a principal player in the development of allograft vasculopathy and allograft failure. The hallmark of endothelial dysfunction is impaired nitric oxide bioavailability. Recent evidence implicates endothelin-1 as an integral component of endothelial dysfunction....

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Bibliographic Details
Main Author: Ramzy, Danny
Other Authors: Rao, Vivek
Format: Others
Language:en_ca
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1807/11250