ASYMMETRIC SYNTHESIS OF SILANEDIOL INHIBITORS FOR ACE, FXIa, AND CHYMASE

Chemistry === Ph.D. === Dialkylsilanediols, a novel class of non-hydrolyzable analogues of the tetrahedral intermediate of amide hydrolysis, have been shown to be good inhibitors of the HIV-1 protease, angiotensin converting enzyme (ACE), thermolysin, and the serine protease α-chymotrypsin...

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Bibliographic Details
Main Author: Duong, Hoan Quoc
Other Authors: Sieburth, Scott McNeill
Format: Others
Language:English
Published: Temple University Libraries 2013
Subjects:
Online Access:http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/227165