ASYMMETRIC SYNTHESIS OF SILANEDIOL INHIBITORS FOR ACE, FXIa, AND CHYMASE
Chemistry === Ph.D. === Dialkylsilanediols, a novel class of non-hydrolyzable analogues of the tetrahedral intermediate of amide hydrolysis, have been shown to be good inhibitors of the HIV-1 protease, angiotensin converting enzyme (ACE), thermolysin, and the serine protease α-chymotrypsin...
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Format: | Others |
Language: | English |
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Temple University Libraries
2013
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Online Access: | http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/227165 |