Epigenetic transcriptional repression of tumor suppresor genes and its reversion by drugs.
Genetic alterations and deregulation of the epigenetic mechanisms collaborate in the initiation and progression of cancer. In contrast to the genetic defects, the epigenetic abnormalities are potentially reversible. This fact has driven the search for drugs that induce selectively changes in the epi...
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| Format: | Doctoral Thesis |
| Language: | English |
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Universitat de València
2005
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| Online Access: | http://hdl.handle.net/10803/9526 http://nbn-resolving.de/urn:isbn:8437062888 |