Genetic architecture of complex disease in humans :a cross-population exploration

Genetic architecture of complex disease in humans :a cross-population exploration

The aetiology of common diseases is shaped by the effects of genetic and environmental factors. Big efforts have been devoted to unravel the genetic basis of disease with the hope that it will help to develop new therapeutic treatments and to achieve personalized medicine. With the development of hi...

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Bibliographic Details
Main Author: Martínez Marigorta, Urko, 1983-
Other Authors: Navarro i Cuartiellas, Arcadi, 1969-
Format: Doctoral Thesis
Language:English
Published: Universitat Pompeu Fabra 2012
Subjects:
Complex disease
Genome-wide association studies
Human populations
Replicability
Genetic architecture of disease
Rare variants
Infinitesimal model
Genomic and personalized medicine
Enfermedades complejas
Estudio de asociación genómica
Poblaciones humanas
Replicabilidad
Arquitectura genética
Variantes raras
Modelo infinitesimal
Medicina personalizada y genómica
575
Online Access:http://hdl.handle.net/10803/96909

Internet

http://hdl.handle.net/10803/96909

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