K(ATP) Channel blockade instructs microglia to foster brain repair and neurogenesis after stroke

Stroke causes CNS injury associated with strong fast microglial activation as part of the inflammatory response. Fast activation of microglia in response to neuronal damage requires the rapid availability of a large amount of energy to trigger diverse cytotoxic or neuroprotective signals. ATP-depend...

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Bibliographic Details
Main Author: Ortega González, Fco. Javier
Other Authors: Rodríguez Allué, Manuel José
Format: Doctoral Thesis
Language:English
Published: Universitat de Barcelona 2012
Subjects:
612
Online Access:http://hdl.handle.net/10803/80811