Use of calix[4]arenes to recover the self-assembly ability of mutated p53 tetramerization domains
Protein-protein interactions are essential in biological processes and thus, they have become very promising therapeutic targets. Nevertheless, the artificial modulation of protein complexes remains a challenge. Since most work to date has been focused on the inhibition of protein-protein interactio...
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| Format: | Doctoral Thesis |
| Language: | English |
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Universitat de Barcelona
2008
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| Online Access: | http://hdl.handle.net/10803/2819 http://nbn-resolving.de/urn:isbn:9788469157725 |