Experimental evolution of TetX2: Correlating changes in fitness to their structural and functional origins

The study of protein evolution and adaptation resides at the junction between the disciplines of biological chemistry and evolutionary biology. We chose the B. thetaiotaomicron tetracycline resistant enzyme TetX2, as our model system to study the biophysical basis for adaptation to antibiotics; a ph...

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Bibliographic Details
Other Authors: Shamoo, Yousif
Format: Others
Language:English
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1911/70481