Multi-stage designs in dose-response studies
Designs are explored that minimize the asymptotic variance of a single parameter in a dose-response study designed to estimate this parameter. An example is a design to find the dose producing 50% response. Uncertainty of parameter values of the dose-response curve is represented as a normal prior d...
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Format: | Others |
Language: | English |
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2009
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Online Access: | http://hdl.handle.net/1911/16671 |