Multi-stage designs in dose-response studies

Designs are explored that minimize the asymptotic variance of a single parameter in a dose-response study designed to estimate this parameter. An example is a design to find the dose producing 50% response. Uncertainty of parameter values of the dose-response curve is represented as a normal prior d...

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Bibliographic Details
Main Author: Spears, Floyd Martin
Other Authors: Brown, Barry W.
Format: Others
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1911/16671